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How the Unique Stages of a Woman's Heart Affect Her Health

Heart disease is gender-blind, affecting women and men at equal rates. But the reasons why women get heart disease may be different from men.

mother and son playing with a toy together at the kitchen table
Updated January 28, 2026

By Rozy D. Dunham, MD, Cardiologist, Virtua Cardiology

Heart disease is gender-blind, affecting women and men at equal rates. Yet, while it’s the leading cause of death for both sexes in the U.S., the reasons why women get it—and what they experience—may be very different from men.

Understanding those differences is essential to the prevention of heart-related illnesses. From societal and lifestyle stressors to hormones, here are some of the factors that can affect a woman’s heart throughout her life—and what can be done to manage them.

How might pregnancy affect the heart?

When a woman reaches childbearing age, pregnancy and delivery pose cardiac risks to both mother and baby. Here are some things you should know about how this life stage could impact heart health:

  • Pregnancy is a stressful time on a woman’s heart, with blood volume increasing by up to 40% to nourish a growing baby. With the heart pumping so much more blood, her heart rate increases and blood vessels dilate to get blood to the uterus. And with her breathing rate increasing as well, the heart is working harder than ever. These heart changes are a normal part of pregnancy but need to be carefully managed.
  • Pregnancy-related high blood pressure—or other pre-existing heart conditions—can be intensely stressful on the heart when expecting and may require the services of a cardiologist and a maternal-fetal medicine physician.

While managing any heart condition during pregnancy can be concerning, serious heart issues can be addressed by working with a specialist. Raise any concerns with your provider to prioritize both your heart health and that of your baby.

What heart conditions can accompany motherhood?

Throughout motherhood, women often put themselves last, after her children, partner, and other loved ones. Juggling the demands of motherhood, career, and caring for others can create overwhelming stress, which could lead to the following effects:

  • Stress raises the heart rate and blood pressure, the heart muscle pumps harder and needs more oxygen to pump the same amount of blood, and, in turn, weakens the heart in the long term.
  • Stress cannot be managed unless a woman makes herself a priority, at least some of the time. 

Here are some tried-and-true methods for managing these stressors:

  • Women can blast stress by spending time with friends who make them laugh and improve their perspective on life’s challenges. Happiness contributes to a healthy heart. 
  • Exercise reduces stress and stress hormones like cortisol, which contributes to belly fat and conditions like metabolic syndrome, a precursor to type-2 diabetes. 
  • Eating nutritious meals with a balance of lean protein, abundant fruits and vegetables, and whole grains extend the benefits of exercise.

What happens with the heart during perimenopause, menopause, and beyond?

On the other side of the childbearing years as estrogen production slows down, cholesterol rates begin to increase.

  • Menopause or perimenopause are critical times in a woman’s life for a serious conversation with her physician about controlling cholesterol with diet, exercise, and lifestyle changes, or some combination of drug therapy if necessary.
  • Reducing cholesterol early may also reduce the potential for stroke and dementia related to cardiovascular disease. Although the gap is narrowing, women still outlive men by about five years. That means more time to develop heart disease.
  • Women are considerably less active than they should be in later years, making them more prone to heart attacks and strokes.

Even small levels of activity make a difference, fending off depression, keeping blood vessels more flexible, and increasing the strength of the heart. Safe physical activity at any age is essential for good cardiac health.

Live wholehearted. Make an appointment with a Virtua cardiologist.

Virtua’s team of more than 100 cardiac experts provides comprehensive cardiac care, from medical cardiology to interventional procedures to advanced cardiac surgery. Schedule an appointment online with a Virtua cardiologist.

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